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KB v Guhle: Missed Pediatric Sepsis, Diagnostic Anchoring, and Catastrophic Injury Damages

Alberta court awards over $16.5 million to child who suffered quadruple amputation after delayed recognition of bacterial superinfection in pediatric RSV.

By Paul Cahill September 23, 2025 23 min read
Case comment on KB v Guhle, 2025 ABKB 472 and 2025 ABKB 474 (Court of King's Bench of Alberta), plaintiff trial win for an 11-month-old child who suffered amputation of portions of all four limbs after delayed recognition of bacterial superinfection in pediatric viral respiratory illness, with damages totalling over $16.5 million including a $9.6 million lifetime support worker component. By Paul Cahill, LSO Certified Specialist in Civil Litigation.

Pediatric sepsis is one of the most challenging diagnostic problems in medicine. Children, particularly young children and infants, often look reasonably well in the early stages of a serious bacterial illness, and the clinical picture can deteriorate rapidly when the body’s compensatory mechanisms are overwhelmed. Most respiratory illnesses in infants are caused by viruses that follow a predictable and self-limited course. A small but important proportion involve bacterial co-infection or superinfection that can become life-threatening within hours. The framework for distinguishing between the common viral course and the rare but serious bacterial deterioration is one of the most carefully developed areas of pediatric and emergency medicine. The standard of care requires structured assessment, careful monitoring, attention to clinical and laboratory signals of deterioration, and a willingness to revise the working diagnosis when the patient’s trajectory does not match the initial impression.

KB v Guhle, 2025 ABKB 472, released by the Court of King’s Bench of Alberta on August 13, 2025, with damages addressed in 2025 ABKB 474 released August 14, 2025, is a recent application of the framework. The plaintiff was an 11-month-old child who presented to a regional hospital with respiratory symptoms in February 2011. The initial diagnosis was viral bronchiolitis caused by respiratory syncytial virus (RSV), the most common respiratory illness of infancy. Over the next three days, the child’s clinical condition deteriorated through a cascade of signs including increasing respiratory distress, mottled skin, and abnormal blood test results. On the fourth day, she developed respiratory failure and was found to be in septic shock from a Group A Streptococcus bacterial superinfection. She was intubated, started on intravenous antibiotics, and transferred to a tertiary pediatric hospital. The infection had already produced devastating compromise of blood flow to her extremities. By the end of March 2011, she had undergone amputation of portions of all four limbs.

After more than 14 years of litigation, the Court of King’s Bench of Alberta found that the standard of care had been breached by the principal treating physician during the in-hospital admission, that the breach had caused the catastrophic outcome, and that damages exceeded $16.5 million. The case is one of the largest pediatric medical malpractice trial awards in recent Canadian history, and the reasoning provides a detailed articulation of several doctrinally important frameworks.

The case is doctrinally important for several reasons. It is one of the clearest recent articulations of the standard of care for pediatric sepsis recognition, including specifically the framework for recognizing bacterial superinfection in patients initially diagnosed with viral respiratory illness. It applies the diagnostic anchoring framework to a missed pediatric sepsis case, illustrating how premature closure on an initial impression can fall below the standard of care when the clinical trajectory does not match. It illustrates the multi-defendant liability allocation framework, with three physicians implicated and only one ultimately found liable. It includes one of the most detailed recent damages assessments in pediatric catastrophic injury litigation, with the future support worker component alone exceeding $9.6 million. And it adds an Alberta authority to the developing cluster of doctrinal frameworks for catastrophic pediatric injury claims.

The clinical context — pediatric respiratory illness, RSV, and bacterial superinfection

A brief clinical overview is useful for the analysis.

Respiratory syncytial virus. RSV is a common respiratory virus that causes the majority of cases of bronchiolitis in children under two years of age. RSV bronchiolitis typically presents with cough, wheezing, fever, and signs of respiratory distress. The natural history is generally self-limited, with most children recovering with supportive care over one to two weeks. A small proportion of children with RSV bronchiolitis become severely ill and require hospitalization, oxygen support, or mechanical ventilation. Infants under six months of age, premature infants, and children with underlying heart or lung conditions are at higher risk for severe RSV.

Bronchiolitis. Bronchiolitis is inflammation of the small airways of the lungs (the bronchioles). The clinical signs include wheezing, increased respiratory effort, retractions (visible drawing in of the chest wall), tachypnea (increased respiratory rate), and signs of oxygen desaturation in more severe cases. The standard of practice for assessment of suspected bronchiolitis includes clinical examination, monitoring of oxygen saturation, and supportive care with oxygen as needed. Routine investigations (chest X-ray, blood work) are not always indicated in straightforward cases, but they are commonly performed in hospitalized children to support the clinical assessment.

Bacterial superinfection. Although the modal course of viral bronchiolitis is self-limited, some children develop bacterial superinfection. The Canadian Pediatric Society guidelines, accepted by both sides at trial, describe bacterial superinfection as rare but recognized. The pattern can involve secondary bacterial pneumonia (with pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, or Group A Streptococcus), bacterial bronchitis, or systemic bacterial infection (bacteremia, septicemia).

The framework recognizes that “rare” does not mean “never.” The standard of practice requires vigilance for the development of bacterial superinfection in any child whose clinical trajectory does not match the expected viral course.

Clinical signs of deterioration. The signs that should raise concern for bacterial superinfection in a child with viral respiratory illness include:

  • Worsening rather than improving respiratory status despite supportive care
  • Persistent high fever or new fever after a period of improvement
  • Mottled skin or other signs of impaired circulation
  • Tachycardia disproportionate to the fever
  • Lethargy or altered mental status
  • Increasing oxygen requirements
  • Abnormal laboratory findings: elevated white blood cell count with left shift, elevated C-reactive protein, abnormal blood gas, signs of metabolic acidosis
  • Persistent or worsening infiltrates on chest X-ray

The framework treats these signs as warranting reassessment of the working diagnosis, consideration of bacterial superinfection, and (where appropriate) escalation of treatment including antibiotic therapy and consultation with specialist support.

Group A Streptococcus and septic shock. Group A Streptococcus (GAS) is a particularly virulent bacterium that can cause severe infections including necrotizing fasciitis, streptococcal toxic shock syndrome, and severe sepsis. In children, GAS can produce a rapidly progressive infection with high mortality and morbidity. The framework for early recognition and treatment is critical because the time window between recognition and effective intervention can determine the outcome.

Septic shock and tissue perfusion. In severe sepsis, the systemic inflammatory response produces vasodilation, fluid leak from blood vessels, and hemodynamic instability. The body’s compensatory mechanisms (tachycardia, redirection of blood flow to vital organs) can maintain blood pressure to a degree, but as the cascade progresses, blood flow to peripheral tissues (limbs, skin, extremities) becomes compromised. The peripheral hypoperfusion can produce mottled skin, cool extremities, and (in severe cases) ischemic injury to the extremities. Where the cascade is not interrupted, the ischemic injury can become irreversible, requiring amputation of the affected tissue.

The diagnostic anchoring problem. Diagnostic anchoring (also called premature closure) is the cognitive bias of fixing on an initial impression and failing to revise it as new information emerges. In pediatric respiratory illness, the anchoring problem typically presents as continued treatment for the initial viral diagnosis even as the child’s clinical trajectory diverges from the expected viral course. The framework for guarding against anchoring includes structured differential diagnosis development, active consideration of “what else could this be?” as the clinical picture evolves, and willingness to revise the working diagnosis when warranted.

The facts

The patient. The plaintiff was an 11-month-old girl with a history of respiratory illnesses. The decision identifies her only by initials, consistent with the publication framework for minors in catastrophic injury cases. For purposes of this analysis she is referred to as KB or the child.

The initial presentation. On February 19, 2011, KB was admitted to a regional hospital in northern Alberta with severe shortness of breath, fever, and respiratory symptoms. The initial assessment supported a diagnosis of RSV bronchiolitis. Supportive care was initiated.

The first three days. Between February 19 and February 22, the clinical picture evolved. Signs of clinical deterioration included labored breathing, mottled skin, and abnormal blood test results. The clinical pattern did not match the expected trajectory of uncomplicated viral bronchiolitis. The contemporaneous record documented the changing clinical features.

The cascade on February 22. By February 22, KB had developed respiratory failure. A diagnosis of severe septic shock was made. Group A Streptococcus was subsequently identified as the causative organism. She was intubated, intravenous antibiotics were initiated, and she was transferred to a tertiary pediatric hospital.

The amputations. The septic shock cascade had already compromised blood flow to KB’s extremities. Despite the intensive treatment at the tertiary hospital, the ischemic injury to her limbs was irreversible. Over the weeks that followed, she underwent amputation of portions of all four limbs. The final amputations were completed by March 28, 2011.

The three physicians. The clinical care across the three days involved three principal physicians:

  • Dr. Belhaj was the admitting physician. He performed the initial assessment, ordered investigations including blood tests and a chest X-ray, and made the initial working diagnosis of RSV bronchiolitis.
  • Dr. Patidar was a pediatric consultant who reviewed the case after admission. He considered the working diagnoses of asthma and RSV bronchiolitis, and on February 22 he suggested starting antibiotics, although the precise nature of this recommendation became a contested issue at trial.
  • Dr. Guhle was the principal treating physician after admission. He was responsible for ongoing monitoring of KB’s condition, review of investigation results, and decisions about escalation of care.

The action. KB, through her litigation guardian, brought a civil action against the three physicians alleging that the standard of care had been breached and that the breaches had caused the catastrophic outcome.

The expert evidence

Both sides called extensive expert evidence on the standard of care and on causation.

The plaintiff’s experts.

An emergency medicine expert with more than thirty years of clinical experience addressed the standard of care for the initial physician’s assessment, history-taking, physical examination, and diagnostic workup. The expert applied the framework for emergency department evaluation of a child with respiratory symptoms.

A pediatric medicine expert with subspecialty training in respiratory disease addressed the appropriate treatment of bronchiolitis in children, the recognition of bacterial superinfection, the standard of practice for managing a child with possible bacterial lung infection, and the expected clinical outcome with appropriate management.

A third expert in pediatric medicine, infectious disease, and microbiology addressed the causal pathway of KB’s illness, including specifically the point in time at which appropriate antibiotic treatment could have prevented the catastrophic outcome.

The defence experts.

A family and emergency medicine expert addressed the standard of care for a family physician practicing in a regional hospital emergency department, including the diagnosis and treatment of respiratory infections in children.

A pediatrician with extensive experience in pediatric respiratory illness addressed the pediatric standard of care, citing the Canadian Pediatric Society guidelines and noting that bacterial superinfection in viral bronchiolitis is rare.

A pediatric infectious disease expert addressed the origin, identification, manifestation, and treatment of infectious diseases, including the efficacy of antibiotic therapy.

A radiologist provided opinion evidence on the interpretation of pediatric chest X-rays and the framework for interdisciplinary communication between radiologists and treating physicians.

The court’s analysis on standard of care

The court applied the standard of care framework to each of the three physicians.

Dr. Belhaj’s care. The court found that Dr. Belhaj had generally met the standard of care for his role. He had ordered appropriate tests and treatments including blood work, chest X-ray, and supportive medications. The court identified some gaps in documentation, including the absence of a documented differential diagnosis that explicitly considered bacterial infection. The court also noted that he had not consulted a radiologist to confirm his interpretation of the chest X-ray. The court characterized his actions as generally consistent with his training and practice.

Dr. Patidar’s care. The court found Dr. Patidar’s role to be more limited (consultative rather than primary treating). He had considered asthma and RSV bronchiolitis as the main diagnoses and had not documented the possibility of bacterial infection until later in the clinical course. His suggestion to start antibiotics on February 22 was not clearly characterized in the contemporaneous record as a firm order, and the antibiotics were not administered before KB’s condition became critical. The court found that there were gaps in communication and documentation but that his conduct was generally consistent with his usual practice.

Dr. Guhle’s care. The court found that Dr. Guhle’s care fell below the standard. As KB’s principal treating physician after admission, he was responsible for ongoing monitoring and for response to clinical signals of deterioration. The court identified several specific failures:

  • Failure to review KB’s earlier chest X-ray (which was part of the contemporaneous evidence about her clinical status)
  • Failure to fully act on abnormal blood test results that could have indicated bacterial infection
  • Persistent reliance on the working diagnosis of viral infection even as the clinical picture diverged from the expected viral course
  • Failure to escalate the treatment plan or to consider the differential diagnosis of bacterial infection until the deterioration on February 22 had become critical

The framework applied by the court is the diagnostic anchoring framework: where the initial working diagnosis is maintained without revision in the face of clinical signals warranting reconsideration, the standard of practice is not met.

The court’s analysis on causation

The court applied the causation framework to each physician whose conduct was reviewed.

Dr. Belhaj. The court found no causation between any documentation gaps and the catastrophic outcome. His investigations and treatment were generally appropriate; the gaps in documentation did not change the clinical trajectory.

Dr. Patidar. The court found that even if Dr. Patidar’s recommendation of antibiotics had been more firmly framed and timely documented, the recommendation was made on February 22 when KB’s condition had already reached a critical point. The earlier intervention that the framework identified as necessary to prevent the catastrophic outcome would have occurred before Dr. Patidar’s involvement on February 22. The court found no causation between Dr. Patidar’s conduct and KB’s injuries.

Dr. Guhle. The court found that Dr. Guhle’s failure to act on the abnormal test results and the worsening clinical picture contributed to the catastrophic outcome. The framework for causation supports the finding because:

  • The expert evidence established that appropriate antibiotic therapy started at the relevant earlier time point would have arrested the bacterial cascade
  • The ischemic injury to KB’s extremities developed during the period when Dr. Guhle was responsible for her care
  • The earlier diagnosis and treatment was within the window during which the cascade could have been interrupted

The combination of breach and causation supported the finding of liability against Dr. Guhle.

The framework illustrates the multi-defendant liability allocation pattern: where multiple physicians are involved in a patient’s care and only one is found to have breached the standard of care in a way that caused the harm, the framework supports liability against only that physician. The framework is consistent with the broader Canadian tort law structure that requires the plaintiff to prove both breach and causation in respect of each defendant.

The damages assessment

The court’s damages assessment in 2025 ABKB 474 provides one of the most detailed recent articulations of the catastrophic pediatric injury damages framework.

General damages: $426,721. The general damages component compensates for pain and suffering and loss of enjoyment of life. The award reflects the catastrophic nature of the injury for a child who will live with the consequences for the rest of her life. The Canadian framework for general damages, since the Andrews v Grand & Toy Alberta Ltd, [1978] 2 SCR 229 trilogy, caps non-pecuniary damages at a figure that is adjusted for inflation. The cap currently stands at approximately $440,000 for catastrophic injury cases. The award in KB v Guhle sits at the upper end of the available range.

Past prosthetic costs: $445,863. This category covers the prosthetic devices that KB had used in the period between her amputations and trial.

Future prosthetic costs: $2,811,480. This category covers the prosthetic devices KB will need over her expected remaining lifespan. Prosthetic devices for upper and lower limbs require replacement at intervals, and the children’s prosthetic needs evolve as the child grows. The future framework includes the lifetime cost of these devices.

Equipment: $1,029,194. This category covers wheelchairs, transfer equipment, environmental control units, communication devices, and other equipment needed for daily living. The equipment needs change over time as KB grows and as her functional capacity evolves.

Support workers: $9,618,408. This is the largest single component of the damages award. The framework reflects the lifetime cost of personal support workers who will assist KB with activities of daily living including dressing, bathing, toileting, meal preparation, mobility, and other functions that the amputations have affected. The framework calculates the hours of support needed, the wage rate, the duration of the lifetime needs, and the appropriate discount rate.

Therapy: $533,330. This category covers ongoing physical therapy, occupational therapy, psychological therapy, and other rehabilitation services. The framework reflects that therapy needs continue throughout life rather than concluding at a specific point.

Home maintenance and modifications: $113,808. This category covers the modifications to the home environment needed to support KB’s mobility and independence, along with the ongoing maintenance costs of those modifications.

Loss of future income: $702,468. This category compensates for the loss of KB’s expected earning capacity over her working life. The framework for assessing loss of future income in a child involves projection of the likely educational and vocational trajectory, comparison with the trajectory after the injury, and calculation of the present value of the difference. The framework includes appropriate adjustments for non-negligent risks of work absence (illness, retirement, and so on).

Total for KB: $15,671,272.

KB’s mother’s damages: $646,025. Under the Alberta Family Law Act, family members can recover for their own pecuniary and non-pecuniary losses arising from a catastrophic injury to a family member. The framework covers out-of-pocket expenses incurred by the family member, the value of past care services they have provided to the injured person, and (where applicable) lost income from time taken from work to provide care.

Crown subrogated interest: $474,314.93. The provincial government’s subrogated interest covers the cost of medical services provided through the public health insurance system. The framework operates similarly to the OHIP subrogated interest in Ontario.

Pre-judgment interest in addition. Interest typically accrues from the date the action was commenced through to the date of judgment. The framework can substantially increase the total recovery in cases with long litigation timelines (such as the 14-year timeline of KB v Guhle).

Total award: over $16.5 million.

The doctrinal anchors

Several doctrinal anchors emerge from the case.

The pediatric sepsis recognition framework. The standard of care for assessment of a child with respiratory illness includes vigilance for the development of bacterial superinfection. Where the clinical trajectory does not match the expected viral course, the framework requires consideration of alternative diagnoses including bacterial infection. KB v Guhle is the principal cluster authority on the framework in a catastrophic outcome context.

The viral-to-bacterial superinfection framework. The Canadian Pediatric Society guidelines describe bacterial superinfection in viral bronchiolitis as rare but recognized. The framework treats “rare” as not equivalent to “never” and requires vigilance for the rare cases. The framework is generalizable across pediatric infectious disease practice.

The diagnostic anchoring framework. Where the initial working diagnosis is maintained without revision in the face of clinical signals warranting reconsideration, the standard of practice is not met. The framework joins the CPSO v Duic application in the emergency medicine context, and the broader Canadian medical malpractice literature on premature closure.

The “failure to review prior imaging” framework. Where a treating physician has access to prior imaging studies that bear on the diagnostic question, the standard of care typically requires review of those studies. KB v Guhle applies the framework to the failure to review an earlier pediatric chest X-ray.

The “failure to act on abnormal lab results” framework. Where laboratory investigations return abnormal results that could indicate a serious diagnosis, the standard of care requires the physician to act on those results, either by consideration of the differential or by escalation of investigation. KB v Guhle applies the framework specifically to elevated inflammatory markers and other abnormalities suggesting bacterial infection.

The multi-defendant liability allocation framework. Where multiple physicians are involved in a patient’s care, the framework requires individual analysis of each physician’s conduct against the standard of care and individual analysis of causation in respect of each. The framework does not impose collective liability; only physicians whose conduct breached the standard and caused the harm can be held liable. KB v Guhle illustrates the framework with three physicians considered and one found liable.

The “rare but recognized” complication framework. Where the medical literature describes a complication as rare but recognized, the standard of care requires the physician to maintain vigilance for it even though it will not occur in most cases. The framework is generalizable across medical specialties.

The pediatric catastrophic injury damages framework. Where a child suffers a catastrophic injury, the damages assessment includes the lifetime cost of care needs that will evolve as the child grows and develops. The framework includes specific consideration of prosthetics, equipment, support workers, therapy, home modifications, and loss of future earning capacity. The framework is one of the most carefully developed areas of Canadian damages assessment.

The Family Law Act parental damages framework. Under the Alberta Family Law Act (and similar legislation in other provinces including the Ontario Family Law Act, s 61), family members can recover for their own losses arising from a catastrophic injury to a family member. The framework typically covers out-of-pocket expenses, the value of past care services, and lost income from time taken from work.

The Crown subrogated interest framework. Where provincial health insurance has paid for medical care related to the underlying injury, the framework supports recovery by the Crown of those costs through a subrogated interest. The framework operates across Canadian jurisdictions with similar consumer protection and cost-recovery rationales.

The “documentation as evidence of reasoning” framework. Where the physician’s contemporaneous documentation does not record the considered differential or the reasoning for the working diagnosis, the framework permits the trier of fact to draw inferences about whether the reasoning actually occurred. KB v Guhle applies the framework alongside CPSO v Duic and other recent cases.

The “long litigation timeline in catastrophic injury cases” framework. Birth injury and catastrophic pediatric injury cases typically take 10 to 15 years from injury to resolution. KB v Guhle illustrates the 14-year timeline. The framework includes the development of the clinical trajectory, the complexity of the expert evidence, the procedural framework for cases involving persons under disability, and the practical realities of preparation for trial.

Why this case matters

For families facing catastrophic pediatric outcomes. The case is a sobering and important precedent. The outcome demonstrates that the catastrophic injury framework can recognize the full scope of lifetime needs and provide a meaningful damages assessment.

Some practical observations:

Early assessment of the clinical record is critical. Where a family suspects that an in-hospital course did not match what should have happened, the contemporaneous clinical record is the principal evidence. The framework for assessment includes review by experienced experts who can identify the specific points at which the standard of care may not have been met. Early assessment supports careful evaluation and (where appropriate) careful framing of the claim.

The diagnostic anchoring framework is well-established. Where a treating physician maintains an initial diagnosis without revision in the face of clinical signals warranting reconsideration, the framework supports the standard of care analysis. The pattern is recognized in the case law and in the medical literature.

The damages framework supports lifetime needs. Where a child is left with permanent and substantial care needs, the framework recognizes the full lifetime cost. The support worker component alone in KB v Guhle exceeded $9.6 million, reflecting the framework for projecting the lifetime cost of personal support.

The litigation timeline is long. Catastrophic pediatric injury cases typically take many years to resolve. The framework requires patience and careful preparation throughout, including review of the underlying clinical evidence, development of the expert evidence, and the practical realities of trial preparation. Families considering these cases should be aware of the timeline.

For more on the general framework for evaluating medical malpractice cases, see Suing for Medical Malpractice in Ontario: What You Need to Know. For more on the framework for declined cases, see Why Many Medical Malpractice Cases Are Declined in Ontario.

For pediatric and emergency medicine teams. A few practical observations:

Vigilance for bacterial superinfection is part of the standard. Even where the initial diagnosis is RSV bronchiolitis (and that diagnosis is consistent with the available evidence), the framework requires ongoing assessment of the clinical trajectory. Where the trajectory does not match the expected viral course, the framework requires reconsideration of the differential.

Document the differential and the reasoning. The framework for the standard of practice includes structured documentation of the differential diagnosis and the reasoning for the working diagnosis. Where the documentation is detailed, the framework supports the standard of care analysis. Where the documentation is sparse, the framework can permit critical inferences.

Review prior imaging. Where prior imaging is available, the framework typically requires the treating physician to review it. The review is part of the integrated picture of the patient’s clinical status.

Act on abnormal lab results. Where laboratory investigations return abnormal results that could indicate a serious diagnosis, the framework requires the physician to act on the results. Acting includes consideration of the differential, escalation of investigation, or escalation of treatment as appropriate.

Be alert to diagnostic anchoring. The structured discipline of considering “what else could this be?” as the clinical picture evolves is a recognized check against premature closure. The framework is part of the broader teaching on cognitive bias in clinical decision-making.


Decision Dates: August 13, 2025 (liability); August 14, 2025 (damages)

Jurisdiction: Court of King’s Bench of Alberta

Citations: KB v Guhle, 2025 ABKB 472 (CanLII) (liability); KB v Guhle, 2025 ABKB 474 (CanLII) (damages)

Outcome: Judgment in favour of the plaintiff against the principal treating physician for breach of the standard of care in failing to recognize and respond to clinical and laboratory signals of bacterial superinfection in an 11-month-old patient admitted with viral bronchiolitis. Two other physicians involved in the patient’s care (the admitting physician and the consulting pediatrician) were considered but were not found liable on either the standard of care or causation analysis. The court awarded damages totalling over $16.5 million, comprising approximately $15.67 million to the catastrophically injured child, $646,025 to her mother under the Alberta Family Law Act, and $474,315 to the Crown for subrogated health care costs, all exclusive of pre-judgment interest. The future support worker component of the child’s damages exceeded $9.6 million, reflecting the lifetime cost of personal support associated with the consequences of the quadruple amputation that followed the septic shock cascade.

Key authorities: Wilson v Swanson, [1956] SCR 804 (specialist standard); Crits v Sylvester, [1956] OR 132 (medical practitioner standard); ter Neuzen v Korn, [1995] 3 SCR 674 (specialist standard); Snell v Farrell, [1990] 2 SCR 311 (robust and pragmatic causation); Clements v Clements, 2012 SCC 32 (but-for causation framework); Andrews v Grand & Toy Alberta Ltd, [1978] 2 SCR 229 (general damages cap framework); Family Law Act, RSA 2003, c F-4.5 (parental damages); Health Care Insurance Act, RSA 2000, c A-20 (Crown subrogated interest framework).

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